RNA Details
Disease Name
neurofibromatosis
Tissue
nerve
RNA Symbol
mir-21a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR; etc.
Target
PTEN
Pathway
NA
PubMed ID
Title
MicroRNA-21 overexpression contributes to vestibular schwannoma cell proliferation and survival
Year
2010
Function
"Because pten regulates signaling through the growth-promoting phosphoinositide 3-kinase;Akt pathway, our findings suggest that mir-21 may be a suitable molecular target for therapies aimed specifically at reducing vs growth."